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Drugs of natural origin, which have roots in many medical traditions, are of inordinate significance due to the substantial growth in usage around the world. In addition, nature-based medicines are the topic of increased inquiry in the quest for novel pharmacophores that hold the prospect of enhanced therapy. The award of the 2015 Nobel Prize in Physiology or Medicine to nature-based drugs Avermectin and Artemisinin, used in the treatment of infections caused by roundworm parasites and malaria, respectively, underscores such trends, and highlights, in particular, the potential value of naturally derived medicines in targeting neglected tropical diseases. This development follows the World Health Organization’s 2008 ratification of The Beijing Declaration, which promotes the safe and effective use of traditional and alternative medicines and calls for greater assimilation of these into national health care systems. Issues of quality, safety, efficacy measurements, commercial production, regulation, and ethics of natural drugs are now, more than ever, of paramount importance.
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