Basic Biostatistics for Geneticists and Epidemiologists (2008)

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‘Biostatistics, far from being an unrelated mathematical science, is a discipline essential to modern medicine – a pillar in its edifice’ (Journal of the American Medical Association (1966) 195: 1145). Today, even more so than forty years ago, anyone who wishes to read the biomedical literature intelligently, especially in the areas of genetics and epidemiology, needs to understand the basic concepts of statistics. It is our hope that this book will provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in these two biomedical areas.

Unlike many other elementary books on statistics, the main focus of this book is not so much on teaching how to perform some of the simpler statistical procedures that may be necessary for a research paper, but rather on explaining basic concepts needed to understand the literature. Many of the simpler statistical procedures are in fact described, but computational details are included in the main body of the text only if they help clarify the underlying principles. We have relegated to the Appendix other details that, if included in the body of the text, would tend to make it difficult for the reader to see the forest for the trees. If you wish to have the details, read the notes in the Appendix concurrently, chapter by chapter, with the rest of the book.

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