Biostatistics-Elsevier Academic Press (2007)

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Our first edition, Introduction to Biostatistics: A Guide to Design, Analysis, and Discovery, was published in 1995 and was well received both by reviewers and readers. That book broke new ground by expanding the range of methods covered beyond what typically was included in competing texts. It also emphasized the importance of understanding the context of a problem — the why and what — instead of considering only the how of analysis.

Although the past several years have seen much interest in a second edition, our involvement with numerous other projects prevented us from tackling a new edition. Now that the stars are in alignment (or whatever), we fi nally decided to create a second edition. We are excited that Mike Hernandez has agreed to collaborate with us on this edition.

This new edition builds on the strengths of the first effort while including several new topics reflecting changes in the practice of biostatistics. Although parts of the second edition still serve as an introduction to the world of biostatistics, other parts break new ground compared to competing texts. For some of these relatively more advanced topics, we strongly advise the reader to consult with experts in the field before setting out on the analyses.

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