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From a personal friend of the author was learnt that a rather common hereditary disease of genetic origins can cause severe weakness of the limbs that required supporting metallic braces to aid simple daily walking. This disease, known as CMT, was recently diagnosed in a personal acquaintance! CMT is one of the most common inherited neurological disorders, affecting approximately 1 in 2,500 people in the United States of America. The disease is named after the three physicians who first identified it in 1886 – Jean-Martin Charcot and Pierre Marie in Paris, France, and Howard Henry Tooth in Cambridge, England. CMT, also known as Hereditary Motor and Sensory Neuropathy (HMSN) or Peroneal Muscular Atrophy (PMA), comprises a group of disorders that affect peripheral nerves. The peripheral nerves lie outside the brain and spinal cord and supply the muscles and sensory organs in the limbs. Disorders that affect the peripheral nerves are called peripheral neuropathies. Although there is no known cure for CMT, physical therapy, occupational therapy, braces and other orthopedic devices, and even orthopedic surgery may help individuals deal with the disabling symptoms of the disease. In addition, pain-killing drugs can be prescribed for individuals who have severe pain.
Physical and occupational therapy, the preferred treatment for CMT, involves muscle strength training, muscle and ligament stretching, stamina training, and moderate aerobic exercise. Most therapists recommend a specialized treatment program designed with the approval of the person’s physician to fit individual abilities and needs. Therapists also suggest entering into a treatment program early as muscle strengthening may delay or reduce muscular atrophy, so strength training is most useful if it begins before nerve degeneration and muscle weakness progresses to the point of disability!
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