Digestive Disease Pathology - Vol 1 (1988) Pdf Free Download

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Overview of Digestive Disease Pathology - Vol 1 (1988) Pdf Free Download:

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Features of Digestive Disease Pathology - Vol 1 (1988) PDF free download:

Most, even all neoplasms are known to show variable degrees of cellular differentiation, not only biologically, but also morphologically.' Thus, we pathologists can recognize the histological type of each tumor on the basis of morphological similarities to its normal or nonneoplastic counterparts. Carcinoma of the stomach, the most common cancer in Japan shows a variety of histological appearances, although it has been roughly grouped into two types, diffuse carcinoma vs. adenoplastic carcinoma. The diffuse cancer is characterized by its scirrhous growth pattern and the occurrence of signet ring cells, a peculiar cancer morphology in the stomach.

The histological heterogeneities of gastric cancer possibly reflect the fact that the gastric mucosa shows a bidirectional cell renewal pattern, (i.e., the generative (stem) cells differentiate upward to the foveolar epithelium and downward to the gastric gland). 6- 9 The frequent occurrence of intestinal metaplasia in the aged gastric mucosa2·10 makes the situation more complicated.

            

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